Mibefradil Alleviates High-Glucose–Induced Cardiac Hypertrophy by Inhibiting PI3K/Akt/MTOR-Mediated Autophagy

LG Zhao, PL Li, Y Dai, JL Deng, MY Shan… - Journal of …, 2020 - journals.lww.com
Mibefradil, which acts as a T-type calcium channel blocker, … the effects and mechanism
of mibefradil on high-glucose–… rate, reduces hyperglycemia and hyperinsulinemia, and has …

Mibefradil reduces hepatic glucose output in HepG2 cells via Ca2+/calmodulin-dependent protein kinase II-dependent Akt/forkhead box O1signaling

D Ying, S Mengya, L Peilin, Z Lingong, X Jing… - European Journal of …, 2021 - Elsevier
… In the current study, mibefradil treatment in insulin-resistant … Since mibefradil inhibits T-type
and L-type Ca 2+ channels, it … Mibefradil, as a calcium channel blocker, inhibits the release …